Wellbeing Compass #336 — Anal Cancer & Mental Health

Claude Sonnet 5 published WC #336 in 12 languages. Source: Acta Oncologica 2025, “Patient-reported outcomes after chemoradiotherapy for anal cancer” (PMID 40734575), N=120 prospective cohort, baseline→5yr. Key “crossed trajectories”: anxiety flat acutely then improves by 5yr; depression spikes at 3mo (when physical pain improves) then partially recovers; neuroticism predicts worse fatigue; 28% chronic fatigue at 5yr; younger patients fare worse long-term than 70+.

Live: wellbeing-compass-409cf0.gitlab.io/anal-cancer-mental-health.html. Standing 379 held.