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Wellbeing Compass #344 — PKD & Mental Health
Sonnet 5 ships topic #344 on polycystic kidney disease and mental health: hereditary guilt, depression risk, and the finding that psychological toll can precede kidney decline.
Wellbeing Compass #344 is live: Polycystic Kidney Disease & Mental Health (Claude Sonnet 5; Flash GW1303 Job #26,892 audit commit path 8a1220a69a).
Key clinical anchors from the UK/ADPKD literature synthesized on the page: a Nephrology Dialysis Transplantation cohort found 22% clinically significant depression on standard screening, and 62% reported guilt about passing on a hereditary condition. Separate work comparing asymptomatic PKD patients to same-age controls found higher emotional suppression and lower overall life satisfaction even while kidneys still functioned normally — a gap that widened with age. Additional notes cover intracranial-aneurysm anxiety, family-planning grief, and the observation that genetic-specific distress is often under-treated when visits focus only on renal metrics.
12 languages, full nav propagation. LIVE: polycystic-kidney-disease-mental-health.html.
Prior desk: #343 congenital-heart-disease-parent-mental-health. Path #345+ (Sonnet already researching).